|
Finding
|
BASDAI
|
BASMI
|
BASFI
|
PatGA
|
PhysGA
|
NRS-P
|
ESR (mm/h)
|
CRP (mg/l)
|
|---|
|
At time point 1a
|
|
Mean ± SD
|
2.5 ± 1.8**
|
2.7 ± 2.0*
|
2.9 ± 2.4**
|
2.6 ± 1.5**
|
2.6 ± 2.1**
|
2.6 ± 2.1**
|
10.5 ± 7.3**
|
3.1 ± 4.2**
|
|
Median
|
2.4
|
2.0
|
2.5
|
4.0
|
2.0
|
2.0
|
8.0
|
1.1
|
|
Range
|
0.0 - 6.8
|
0.0 - 7.0
|
0.0 - 8.3
|
0.0 - 8.0
|
0.0 - 4.0
|
0.0 - 7.0
|
2.0 - 32.0
|
0.0 - 19.0
|
|
At time point 2a
|
|
Mean ± SD
|
6.1 ± 1.4**
|
3.2 ± 2.2*
|
5.8 ± 1.8**
|
6.9 ± 2.1**
|
7.0 ± 1.5**
|
7.1 ± 1.7**
|
31.5 ± 29.7**
|
20.7 ± 23.7**
|
|
Median
|
6.2
|
3.0
|
5.7
|
7.0
|
7.0
|
7.0
|
23.0
|
14.0
|
|
Range
|
4.0 - 9.2
|
0.0 - 9.0
|
1.2 - 9.1
|
4.0 - 10.0
|
4.0 - 10.0
|
0.0 - 10.0
|
4.0 - 150.0
|
0.3 - 126.0
|
|
Change between time points 1 and 2
|
|
Mean ± SD
|
3.6 ± 1.7
|
0.5 ± 1.5
|
2.9 ± 2.0
|
4.3 ± 1.9
|
4.4 ± 1.8
|
4.5 ± 2.2
|
21.0 ± 29.7
|
17.6 ± 23.4
|
|
Median
|
3.6
|
0.5
|
2.5
|
4.0
|
4.0
|
4.0
|
12.0
|
11.5
|
|
Range
|
-1.2 - 6.7
|
-4.0 - 3.0
|
-0.5 - 7.8
|
-2.0 - 8.0
|
-2.0 - 8.0
|
-1.0 - 8.0
|
-6.0 - 146.0
|
-6.3 - 123.0
|
- aTime point 1 is the time point at which infliximab treatment was discontinued; time point 2 is that when retreatment began. *P < 0.05, **P < 0.001, when means at time points 1 and 2 are compared. BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Function Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; NRS-P, numerical rating scale for pain; PatGA, patient's global assessment; PhysGA, physician's global assessment; SD, standard deviation.
