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Table 2 T cell receptor Vα24 usage in peripheral blood mononuclear cells, synovial fluid mononuclear cells and synovial tissue from rheumatoid arthritis patients

From: Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis

  Vα24 Vβ11
  PBMCs SFMCs ST PBMCs SFMCs ST
RA 1 mono mono NA oligo (2) mono NA
RA 2 mono poly oligo (2) mono poly oligo (2)
RA 3 mono oligo (2) NA Poly oligo (2) NA
RA 4 poly poly NA Poly poly NA
RA 5 oligo (3) NA mono mono NA mono
RA 6 poly NA poly poly NA poly
RA 7 oligo (3) NA mono poly NA oligo (3)
  1. The clonality of the T-cell receptor (TCR) Vα24 family was assessed by CDR3 spectratyping of peripheral blood mononuclear cells (PBMCs), synovial fluid mononuclear cells (SFMCs) and synovial tissue (ST) from rheumatoid arthritis (RA) patients. (See Fig. 1 for representative monoclonal [panel a], oligoclonal [panel b] and polyclonal [panel c] profiles.) mono, monoclonal profile; NA, not available; oligo, oligoclonal profile; poly, polyclonal profile.