Figure 1From: Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severityVerification of citrullination of collagen type II (CII) and rat serum albumin (RSA) by immunoblotting. Using the recombinant anti-citrullinated protein antibody RA3, citrulline was detected in the citrullinated CII (Cit-CII) sample (upper left) as well as in the citrullinated RSA (Cit-RSA) sample (upper right), while uncitrullinated CII (lower left) and uncitrullinated RSA (lower right) were negative for citrulline.Back to article page