|
Marker
|
SpA (n = 50)
|
RA (n = 52)
|
P
|
|---|
|
Lining layer thickness
|
1.0 (1.0–2.5)
|
2.0 (0–3.0)
|
0.006
|
|
Vascularity
|
2.0 (1.0–3.0)
|
1.5 (1.0–3.0)
|
<0.001
|
|
Cellular infiltration
|
1.5 (0–3.0)
|
2.0 (0–3.0)
|
0.120
|
|
Lymphoid follicles
|
0 (0–3.0)
|
0 (0–3.0)
|
0.232
|
|
Plasma cells
|
0.5 (0–3.0)
|
0.5 (0–3.0)
|
0.497
|
|
Polymorphonuclear cells
|
0 (0–3.0)
|
0 (0–2.5)
|
0.008
|
|
CD3
|
1.5 (0–3.0)
|
2.0 (0–3.0)
|
0.152
|
|
CD4
|
1.0 (0–3.0)
|
1.0 (0–3.0)
|
0.192
|
|
CD8
|
1.0 (0–3.0)
|
1.5 (0–3.0)
|
0.737
|
|
CD20
|
1.0 (0–3.0)
|
2.0 (0–3.0)
|
0.231
|
|
CD38
|
1.5 (0–3.0)
|
2.0 (0–3.0)
|
0.060
|
|
CD138
|
1.0 (0–3.0)
|
2.0 (0–3.0)
|
0.447
|
|
CD68 lining
|
1.0 (0–3.0)
|
1.0 (0–3.0)
|
0.631
|
|
CD68 sublining
|
1.5 (0–3.0)
|
1.5 (0.5–3.0)
|
0.957
|
|
CD163 lining
|
2.0 (0–3.0)
|
1.5 (0–3.0)
|
0.033
|
|
CD163 sublining
|
1.5 (0–3.0)
|
1.0 (0–2.5)
|
0.031
|
|
CD1a
|
0 (0–3.0)
|
1.0 (0–3.0)
|
0.121
|
|
CD83
|
0 (0–1.0)
|
0 (0–3.0)
|
0.006
|
|
CD146
|
2.0 (0–3.0)
|
0 (0–3.0)
|
0.075
|
|
αVβ3 lining
|
1.0 (0–3.0)
|
1.0 (0–3.0)
|
0.397
|
|
αVβ3 sublining
|
1.0 (0–3.0)
|
1.0 (0–3.0)
|
0.306
|
|
E-selectin blood vessels
|
1.0 (0–3.0)
|
1.5 (0–3.0)
|
0.760
|
|
ICAM-1 lining
|
3.0 (1.0–3.0)
|
2.5 (0–3.0)
|
0.025
|
|
ICAM-1 sublining
|
2.0 (0–3.0)
|
2.0 (0–3.0)
|
0.654
|
|
ICAM-1 blood vessels
|
2.5 (0.5–3.0)
|
2.5 (0–3.0)
|
0.652
|
|
VCAM-1 lining
|
3.0 (0–3.0)
|
3.0 (0–3.0)
|
0.077
|
|
VCAM-1 sublining
|
1.5 (0–3.0)
|
1.5 (0–3.0)
|
0.473
|
|
VCAM-1 blood vessels
|
1.0 (0–3.0)
|
1.5 (0–3.0)
|
0.997
|
|
Intracellular citrullinated proteins
|
0%
|
44%
|
<0.001
|
|
Mab-12A
|
0%
|
46%
|
<0.001
|
- The Mann–Whitney U-test was used to evaluate markers scored semiquantitatively, and the χ2 test was used to evaluate markers scored as present or absent. Results are expressed as median (range), and markers evaluated as present or absent are expressed as percentage of positive results. P < 0.05 was considered statistically significant. AS, ankylosing spondylitis; ICAM, intercellular adhesion molecule; PsA, psoriatic arthritis; RA, rheumatoid arthritis; USpA, undifferentiated spondyloarthropathy; VCAM, vascular cell adhesion molecule.
