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Table 3 FBAT-e analyses conducted in 226 ankylosing spondylitis nuclear families (201 pedigrees, 894 persons)

From: ANKHvariants associated with ankylosing spondylitis: gender differences

Marker Allele Allele frequency Number of informative families Z score P
Additive model: biallelic test
   D5S1953 2 0.45 54 0.57 0.569
   rs26307 C 0.81 35 1.73 0.084
   rs27356 C 0.80 39 2.54 0.011*
   3088132 G 0.79 28 1.28 0.198
   rs153929 A 0.76 48 1.61 0.107
   rs258215 A 0.59 43 1.58 0.113
   rs28006 C 0.74 34 1.62 0.104
   rs25957 C 0.76 36 2.02 0.043*
   ANKH-OR 1 0.47 59 1.62 0.105
   D5S1991 2 0.48 58 1.33 0.181
   D5S1954 1 0.64 54 0.65 0.515
Recessive model: biallelic test
   D5S1953 2 0.43 48 0.45 0.683
   rs26307 C 0.80 40 1.49 0.137
   rs27356 C 0.79 44 2.32 0.020*
   3088132 G 0.79 31 1.19 0.233
   rs153929 A 0.76 50 1.86 0.062
   rs258215 A 0.58 32 1.55 0.120
   rs28006 C 0.74 37 1.46 0.142
   rs25957 C 0.76 38 1.65 0.098
   ANKH-OR 2 0.52 37 -2.20 0.027*
   D5S1991 1 0.52 45 -1.96 0.050*
   D5S1954 1 0.64 54 0.65 0.517
  1. *Statistically significant findings. FBAT, family-based association testing.