ANKHvariants associated with ankylosing spondylitis: gender differences

Table 3 FBAT-e analyses conducted in 226 ankylosing spondylitis nuclear families (201 pedigrees, 894 persons)

Marker	Allele	Allele frequency	Number of informative families	Z score	P
Additive model: biallelic test
D5S1953	2	0.45	54	0.57	0.569
rs26307	C	0.81	35	1.73	0.084
rs27356	C	0.80	39	2.54	0.011*
3088132	G	0.79	28	1.28	0.198
rs153929	A	0.76	48	1.61	0.107
rs258215	A	0.59	43	1.58	0.113
rs28006	C	0.74	34	1.62	0.104
rs25957	C	0.76	36	2.02	0.043*
ANKH-OR	1	0.47	59	1.62	0.105
D5S1991	2	0.48	58	1.33	0.181
D5S1954	1	0.64	54	0.65	0.515
Recessive model: biallelic test
D5S1953	2	0.43	48	0.45	0.683
rs26307	C	0.80	40	1.49	0.137
rs27356	C	0.79	44	2.32	0.020*
3088132	G	0.79	31	1.19	0.233
rs153929	A	0.76	50	1.86	0.062
rs258215	A	0.58	32	1.55	0.120
rs28006	C	0.74	37	1.46	0.142
rs25957	C	0.76	38	1.65	0.098
ANKH-OR	2	0.52	37	-2.20	0.027*
D5S1991	1	0.52	45	-1.96	0.050*
D5S1954	1	0.64	54	0.65	0.517

ISSN: 1478-6362