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Table 4 Number of patients and biomarkers of endothelial dysfunction by sex, race, diabetes and medications used

From: Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis

 

Number

VCAM-1 (pg/ml)

ICAM-1 (pg/ml)

ELAM-1 (pg/ml)

Sex

    

Female

64

750 (391–2073)

356 (135–993)

58 (12–144)

Male

10

698 (463–1814)

480 (235–805)

60 (38–149)

Race

    

Caucasian

68

750 (391–2073)

366 (135–993)

61 (12–149)

Asian

6

572 (463–971)

352 (235–699)

49 (35–82)

Diabetes

    

Yes

5

674 (554–1338)

376 (235–455)

55 (52–129)

No

69

749 (391–2073)

365 (135–993)

59 (12–149)

COX-2 inhibitor use

    

Yes

20

689 (475–2073)

371 (145–749)

79 (25–129)

No

54

750 (391–2001)

363 (135–993)

55 (12–149)

Traditional NSAID use

    

Yes

19

766 (493–2001)

366 (135–993)

68 (16–149)

No

55

703 (391–2073)

365 (145–761)

55 (12–129)

Aspirin use

    

Yes

6

719 (463–2073)

346 (219–595)

40 (23–94)

No

68

747 (391–2001)

366 (135–993)

62 (12–149)

Oestrogen use

    

Yes

24

673 (445–2001)

311 (181–993)

53 (12–83)

No

50

786 (391–2073)

389 (135–805)

64 (20–149)

DMARD use

    

Yes

56

726 (391–2073)

368 (145–805)

56 (12–149)

No

18

816 (567–2001)

358 (135–993)

64 (34–115)

Prednisone use

    

Yes

11

930 (391–2073)

455 (181–761)

94 (23–129)

No

63

724 (445–2001)

361 (135–993)

55 (12–149)

Antihypertensive agent use

    

Yes

23

744 (569–2073)

414 (219–805)

66 (16–149)

No

51

758 (391–2001)

350 (135–993)

54 (12–137)

  1. Results for biomarkers are expressed as median (range). Data were analyzed using the Mann–Whitney U test. No comparisons were significant at P ≤ 0.01. COX-2, cyclooxygenase-2; DMARD, disease-modifying antirheumatic drug; ELAM, endothelial leukocyte adhesion molecule; ICAM, intercellular adhesion molecule; NSAID, nonsteroidal anti-inflammatory drug; VCAM, vascular adhesion molecule.