Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis

Table 5 Partial correlation coefficients between IL-6, rheumatoid factor and glomerular filtration rate, and biomarkers of endothelial dysfunction in rheumatoid arthritis patients

Marker	IL-6		Rheumatoid factor		GFR
	R^a	P	R^a	P	R^a	P
VCAM-1 (pg/ml)	0.262	0.04	0.345	0.006	-0.299	0.02
ICAM-1 (pg/ml)	0.263	0.04	0.373	0.003	-0.351	0.005
ELAM-1 (pg/ml)	0.430	0.0005	0.222	0.09	-0.223	0.07

^aThe correlation coefficients shown are controlled for traditional risk factors (age; sex; race; smoking, alcohol and exercising status; diabetes; waist; systolic blood pressure; total cholesterol; high-density lipoprotein cholesterol; triglycerides) in multivariable regression models. ELAM, endothelial leukocyte adhesion molecule; GFR, glomerular filtration rate; ICAM, intercellular adhesion molecule; IL, interleukin; VCAM, vascular adhesion molecule.

ISSN: 1478-6362