Table 1 Characteristics of the patients enrolled in the study
Diagnosis | No. | Age | Sex (M/F) | Serum HO-1 (ng/ml) | Serum ferritin (ng/ml) |
|---|---|---|---|---|---|
Hemophagocytic syndrome | 7 | 42.7 (15.5) | 1/6 | 71.2 (72.7) | 8485.3 (8388.0) |
Adult-onset Still's disease | 10 | 41.0 (11.9) | 5/5 | 102.8 (102.6) | 9658.5 (17042.1) |
Rheumatic diseases | 73 | 48.2 (15.9) | 22/51 | 3.4 (2.7) | 225.5 (709.9) |
   Rheumatoid arthritis | 30 | 53.1 (13.2) | 8/22 | 2.8 (1.4) | 83.0 (95.3) |
   Systemic lupus erythematosus | 18 | 38.0 (16.8) | 1/17 | 3.2 (1.9) | 188.0 (286.3) |
Active | 12 | 42.5 (16.4) | 1/11 | 3.6 (2.1) | 220.4 (329.8) |
Inactive | 6 | 29.0 (15.1) | 0/6 | 2.2 (1.0) | 100.6 (122.1) |
   Behçet's disease | 16 | 47.3 (14.4) | 10/6 | 2.4 (0.8) | 48.3 (43.0) |
Active | 6 | 46.5 (14.3) | 5/1 | 2.5 (0.5) | 61.4 (45.8) |
Inactive | 10 | 47.7 (15.3) | 5/5 | 2.3 (1.0) | 40.4 (41.7) |
   Dermatomyositis/polymyositis | 9 | 54.4 (16.6) | 3/6 | 7.4 (5.2) | 1097.2 (1827.9) |
Liver diseases | 20 | 47.8 (18.1) | 16/4 | 3.7 (2.4) | 1032.2 (2496.9) |
   Acute hepatitis | 5 | 27.8 (5.6) | 4/1 | 4.8 (3.9) | 1347.0 (861.0) |
   Chronic hepatitis | 7 | 51.9 (12.5) | 6/1 | 3.8 (1.6) | 159.9 (128.0) |
   Liver cirrhosis | 2 | 69.0 (7.1) | 2/0 | 5.8 (1.4) | 102.0 (28.3) |
   Hepatocellular carcinoma | 2 | 59.5 (10.6) | 2/0 | 1.9 (0.7) | 260.0 (134.4) |
   Primary biliary cirrhosis | 2 | 46.0 (21.2) | 1/1 | 2.8 (3.0) | 373.5 (892.4) |
   Autoimmune hepatitis | 1 | 34 | 0/1 | 2.9 | 11262 |
   Alcoholic hepatitis | 1 | 71 | 1/0 | 2.8 | 56 |
Hematological diseases | 10 | 62.3 (15.3) | 6/4 | 4.3 (2.4) | 2822.6 (2817.3) |
   Myelodysplastic syndrome | 6 | 59.3 (22.5) | 4/2 | 3.7 (2.6) | 1883.8 (1885.9) |
   Aplastic anemia | 4 | 54.0 (18.8) | 2/2 | 5.1 (2.1) | 4230.8 (3671.1) |
Healthy controls | 22 | 30.8 (7.6) | 16/6 | 2.6 (1.3) | 93.0 (56.9) |