SELDI-TOF MS profiles for patients with SJIA treated conventionally. Six serum protein peaks can be clearly seen to have changed after conventional therapy. The profiles of a representative patient are shown here. Visually distinct peaks that were clearly different between pre- and post-treatment paired samples upon visual inspection of the profiles (in bold type in Table 1) are outlined in grey. Pre- and post-treatment spectra are shown on the same intensity scale in each frame. SELDI-TOF MS, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry SJIA, systemic juvenile idiopathic arthritis.