From: Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody
Before therapy
7 months after therapy
n
Mutations (n)
Total bp
Mutational frequency (%)
CD19+CD27-
18
27
4,349
0.62
15
183
3,443
5.31*
CD19+CD27+
Not determined
22
477
5,745
8.30