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Table 1 Unanswered questions about B cell therapies

From: B cell targeted therapies

What is the duration of clinical efficacy after a single course of rituximab? Belimumab?

Is there a need for concomitant corticosteroids with each course of corticosteroids?

What are the long-term implications of CD20+ B cell depletion?

Is there a risk for increased occurrence of serious infections with B cell targeted therapies? Opportunistic infections?

What role might biologics play in combination with B cell targeted therapies?

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Arthritis Research & Therapy

ISSN: 1478-6362

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