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Table 3 Nuclear mutational burden data of OA and RA patient tissue and cultured fibroblasts

From: Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes

Patients Nucleotides sequenced Number of total mutations Total mutational burden (mutations/kbp) Number of amino acid changes Expressed mutational burden (mutations/kbp) OA vs RAa
Fibroblasts       
   OA 10971 36 3.281 24 2.188  
   RA 7317 15 2.050 10 1.367 ρ = 0.2
Tissue       
   OA 18287 32 1.750 15 0.820  
   RA 24522 41 1.672 21 0.856 ρ = 0.2
  1. aTwo-tailed Fisher's exact test. kbp, kilobase pairs; OA, osteoarthritis; RA, rheumatoid arthritis.