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Table 2 Characteristics of bone marrow lymphocytes were influenced both by ovariectomy and by arthritis

From: Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation

Arthritis

OVX

n

Bone marrow cellularity (Ă— 106)

B cells per femur (Ă— 106)

T cells per femur (Ă— 106)

CD4+ cells per femur (Ă— 106)

CD69+/CD4+ cells (%)

CD8+ cells per femur (Ă— 106)

CD69+/CD8+ cells (%)

-

-

10

5.1 (4.0–6.4)

1.5 (1.0–1.7)***

0.06 (0.05–0.09)

0.02 (0.02–0.04)

25 (18–30)

0.013 (0.008–0.018)

3 (1–3)

 

+

10

6.0 (5.0–8.6)

2.4 (2.0–3.0)

0.05 (0.04–0.07)

0.02 (0.02–0.03)

29 (26–31)

0.008 (0.006–0.012)

4 (2–6)

+

-

18

5.2 (4.7–7.0)

1.0 (0.8–1.3)**†

0.05 (0.04–0.06)

0.02 (0.01–0.02)

50 (43–58)***†††

0.004 (0.002–0.007)†††

9 (4–25)†††

 

+

15

6.1 (5.3–8.4)

1.5 (1.0–2.5)†

0.05 (0.03–0.05)

0.02 (0.01–0.02)

35 (29–40)

0.005 (0.002–0.006)†††

10 (5–16)†

  1. Values are medians and interquartile ranges for each group; n is the number of mice. Comparison between sham operation and ovariectomy (OVX): **P < 0.01; ***P < 0.001. Comparison between arthritic mice and their controls: †P < 0.05; †††P < 0.001.