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Table 2 Characteristics of bone marrow lymphocytes were influenced both by ovariectomy and by arthritis

From: Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation

Arthritis OVX n Bone marrow cellularity (× 106) B cells per femur (× 106) T cells per femur (× 106) CD4+ cells per femur (× 106) CD69+/CD4+ cells (%) CD8+ cells per femur (× 106) CD69+/CD8+ cells (%)
- - 10 5.1 (4.0–6.4) 1.5 (1.0–1.7)*** 0.06 (0.05–0.09) 0.02 (0.02–0.04) 25 (18–30) 0.013 (0.008–0.018) 3 (1–3)
  + 10 6.0 (5.0–8.6) 2.4 (2.0–3.0) 0.05 (0.04–0.07) 0.02 (0.02–0.03) 29 (26–31) 0.008 (0.006–0.012) 4 (2–6)
+ - 18 5.2 (4.7–7.0) 1.0 (0.8–1.3)** 0.05 (0.04–0.06) 0.02 (0.01–0.02) 50 (43–58)***††† 0.004 (0.002–0.007)††† 9 (4–25)†††
  + 15 6.1 (5.3–8.4) 1.5 (1.0–2.5) 0.05 (0.03–0.05) 0.02 (0.01–0.02) 35 (29–40) 0.005 (0.002–0.006)††† 10 (5–16)
  1. Values are medians and interquartile ranges for each group; n is the number of mice. Comparison between sham operation and ovariectomy (OVX): **P < 0.01; ***P < 0.001. Comparison between arthritic mice and their controls: P < 0.05; †††P < 0.001.