Table 1 Summary of adhesion molecules and chemokines/cytokines differentially expressed in CIA joints at early stages of disease and their GO terms.
From: Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis
Affymetrix ID | Change | Gene ID | Description | Go Term/Function |
|---|---|---|---|---|
Solely changed in comparison CFA/collagen II versus CFA | ||||
1423760_at | Up | Cd44 | CD44 antigen | GO:0007155 cell adhesion |
Solely changed in comparison CFA/collagen II versus no treatment | ||||
1422103_a_at | Dn | Stat5b | Signal transducer and activator of transcription 5B | GO:0030155 cell adhesion |
1423166_at - | Dn | Cd36 | CD36 antigen | GO:0007155 cell adhesion |
1427165_at - | Up | Il13ra1 | IL-13 receptor alpha 1 | GO:0004907 IL activity |
1434044_at - | Dn | Repin1 | Replication initiator 1 | GO:0006954 inflammatory response |
1452483_a_at | Up | Cd44 | CD44 antigen | GO:0007155 cell adhesion |
1452514_a_at | Dn | Kit | Kit oncogene | GO:0006935 chemotaxis |
Solely changed in comparison CFA versus no treatment | ||||
1416156_at | Dn | Vcl | Vinculin | GO:0005912 adherens junction |
1417705_at | Dn | Otub1 | OTU domain, ubiquitin aldehyde binding 1 | GO:0006955 immune response |
1422873_at | Dn | Prg2 | Proteoglycan 2, bone marrow | GO:0006955 immune response |
1430375_a_at | Up | Ccl27 | Chemokine (CC motif) ligand 27 | GO:0008009 chemokine activity |
1437807_x_at | Dn | Catna1 | Catenin α1 | GO:0005912 adherens junction |
1452020_a_at | Up | Siva | CD27 binding protein | GO:0005175 CD27 receptor binding |
1455158_at | Dn | Itga3 | Integrin α3 | GO:0007155 cell adhesion |
Changed in comparisons CFA/collagen II vs. CFA and CFA vs. no treatment | ||||
1450488_at | Dn-Up | Ccl24 | Chemokine (CC motif) ligand 24 | GO:0008009 chemokine activity |
Changed in comparisons CFA/collagen II vs. no treatment and CFA vs. no treatment | ||||
1419329_at | Dn Dn | Sh3d4 | SH3 domain protein 4 | GO:0007155 cell adhesion |
1420465_s_at | Up Up | Mup1 | Major urinary protein 1 | GO:0016068 type I hypersensitivity |
1420553_x_at | Dn Dn | Serpina1a | Serine proteinase inhibitor, clade A, member 1a | GO:0006953 acute-phase response |
1423017_a_at | Up Up | Il1rn | IL-1 receptor antagonist | GO:0006955 immune response |
1423734_at | Up Up | Rac1 | RAS-related C3 botulinum substrate 1 | GO:0007155 cell adhesion |
GO:0006954 inflammatory response | ||||
1423885_at | Dn Dn | Lamc1 | Laminin γ1 | GO:0007155 cell adhesion |
1427164_at | Up Up | Il13ra1 | IL-13 receptor α1 | GO:0004907 IL activity |
1435148_at | Dn Dn | Atp1b2 | ATPase, Na+/K+ transporting, β2 polypeptide | GO:0007155 cell adhesion |
1448303_at | Dn Dn | Gpnmb | Glycoprotein nmb | GO:0007155 cell adhesion |
1451767_at | Up Up | Ncf1 | Neutrophil cytosolic factor 1 | GO:0006954 inflammatory response |