Figure 1

Histology. Representative histology of medial (a, b) and (c–f) lateral tibial plateau cartilage from nonoperated control (panels a and c) and meniscectomized (panels b and d-f) ovine stifle joints. Cell cloning is a prominent feature in the lateral tibial plateau following meniscectomy (asterisk). Osteophyte formation is evident at the lateral joint margin (panel f, arrowheads), and the area of most severe cartilage damage with surface fibrillation (rectangle, panel e) and the adjacent area (circle, panel d) are indicated. Toluidine blue-fast green stain. Scale bar: 250 μm.