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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis

Figure 1

Acquisition, analysis and output for a digital image analysis system. Acquisition and analysis of immunohistochemical staining of CD3+ T lymphocytes in synovial tissue using a digital image analysis system [10]. Three different areas from each biopsy sample, which are representative of the whole tissue section are selected. During analysis, staining thresholds are set for primary staining (i.e. CD3+ T lymphocytes), nuclear staining and background staining. The output is generated in a spreadsheet as the total number of positive cells per square millimetre of synovial tissue.

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Arthritis Research & Therapy

ISSN: 1478-6362

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