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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations

Figure 2

Anti- Nedd5 C-ter antibodies in patients with SLE with and without psychiatric manifestations. Dot plot of anti-Nedd5 C-ter IgG in systemic lupus erythematosus (SLE) patients with psychiatric manifestations (group A, n = 17), in SLE patients without psychiatric manifestations other than anxiety (group B, n = 34), in systemic sclerosis (SSc) patients (n = 20), and in patients with infectious mononucleosis (n = 20). Each dot represents a subject. The samples were considered positive when their optical density was higher than the cutoff value (mean + 2 SD for 35 healthy controls). The broken line represents the cutoff (0.18). *Group A vs group B, P = 0.04; #group A vs infectious mononucleosis, P = 0.034; °group A vs healthy controls, P = 0.003; ^SSc patients vs group B, P = 0.046; §SSc patients vs healthy controls, P = 0.003 (Student's t-test).

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