Figure 1From: NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritisKnee joints, 3 days after induction of ICA in p47phox-/- mice and their WT controls. The numbers of cells present in the synovium (infiltrate) and in the joint cavity (exudate) were determined on an arbitrary scale from 0 to 3: 0, no cells; 1, few; 2, moderate; 3, maximal. The number of cells was determined by two blinded observers. Data are means ± SD for eight animals. Significance was tested with the Wilcoxon rank test (*P < 0.05).Back to article page