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Figure 4 | Arthritis Research & Therapy

Figure 4

From: NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritis

Figure 4

Proteoglycan loss from various cartilage layers of inflamed knee joints. Loss of red staining was scored in tibia, femur and patella on an arbitrary scale from 0 to 3. Data are expressed as loss of red staining in comparison with control cartilage layers, and are means ± SD for eight mice; they were tested for significance with the Wilcoxon rank test (*P < 0.05). No significant difference in proteoglycan loss was found on day 3 (a) or day 7 (b) between wild-type controls and p47phox-/- mice. LF, lateral femur; LT, lateral tibia; MF, medial femur; MT, medial tibia; P, patella.

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Arthritis Research & Therapy

ISSN: 1478-6362

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