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Figure 8 | Arthritis Research & Therapy

Figure 8

From: NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritis

Figure 8

mRNA levels of various FcγRs in synovia derived from inflamed knee joints. Inflamed synovia were isolated 7 days after IFN-γ-stimulated arthritis. The cycle threshold value (Ct) of the various FcγR genes was corrected for glyceraldehyde-3-phosphate dehydrogenase content and for values at zero time. Note that at day 7 significantly lower levels of FcγRI and elevated levels of FcγRII and FcγRIII were found in p47phox-/- mice than in controls.

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