Figure 10
Effect of treatment on CXCR3 and CXCR5 expression. Data are shown for healthy individuals, untreated patients with rheumatoid arthritis and patients treated with corticoid and/or non-steroidal anti-inflammatory drugs or treatment with anti-tumor necrosis factor-α therapy. The percentage of CXCR3hi and CXCR5+ B cells is shown for total B cells and the subpopulation of naive B cells. Box plots show the median values, 25th and 75th quartile and the range of values. Significant differences from controls are shown (*P < 0.05, **P < 0.005). Con, control; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus.