Figure 2

The frequency of B cells in healthy individuals and the different patient groups. (a) Triple staining with CD19, CD20 and CD27 was used to define naive B cells, memory B cells and plasma cells. Thresholds for CD27^-, CD27⁺ and CD27^hi are indicated. (b) Frequency for B cells and the different subpopulations. Data are given for healthy individuals (con) and for each of the patient groups analyzed: osteoarthritis (OA), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Box plots show the median values, 25th and 75th quartile and the range of values. Significant differences from controls are shown (*P < 0.05, **P < 0.005, ***P < 0.0005).