Nailfold capillaroscopy of (a) normal and (b,c) dcSSc patients. In the active pattern of capillary damage, frequent giant capillaries are present ((b) arrow) accompanied by moderate capillary loss and disorganisation of capillary architecture. Late disease pattern was characterized by severe capillary disorganisation with loss of capillaries ((c) arrow). Magnification ×150. dcSSc, diffuse cutaneous systemic sclerosis.