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Table 1 Clinical and serological characteristics of SSc patients

From: Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis

Characteristics

Fibrotic (n = 10)

Atrophic (n = 6)

Mean age (range)

54 (39–72)

58 (37–69)

Mean disease duration, months (range)

11 (4–18)

96 (36–168)

Male/female

2/8

0/6

Organ involvement

  

Mean skin score (range)

33 (19–41)

17 (11–24)

Oesophageal

7/10

3/6

Other gastrointestinal

4/10

1/6

Lung

4/10

2/6

Muscle

3/10

0/6

Renal

2/10

1/6

Cardiac

0/10

1/6

Pulmonary hypertension

2/10

0/6

Serology

  

Antinuclear

10/10

6/6

Anti-topoisomerase 1

4/10

3/6

Anti-RNA polymerase I/III

2/10

1/6

Anti-nuclear RNP

1/10

1/6

Microvascular damage

  

Structural capillary damage

10/10

6/6

  1. RNP, ribonuclear protein; SSc, systemic sclerosis.