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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Sex hormone modulation of cell growth and apoptosis of the human monocytic/macrophage cell line

Figure 4

Poly-ADP-ribose polymerase (PARP)-cleaved expression in cultured human THP-1 cell line. (a) Poly-ADP-ribose polymerase (PARP)-cleaved expression in the cultured human THP-1 cell line in basal conditions and after 168 hours of hormonal treatment and staurosporine (stau). Results are expressed as the mean ± standard deviation of the percentage of the positive area for 100 cells in five different experiments. Bottom: western blot analysis related to PARP-cleaved expression in untreated cells (basal condition) and cells treated with hormones and staurosporine. (b) PARP-cleaved expression in THP-1 cells (basal condition). (c) PARP-cleaved expression in THP-1 cells after normal medium. (d) PARP-cleaved expression in THP-1 cells after testosterone (T) treatment. (e) PARP-cleaved expression in THP-1 cells after 17β-oestradiol (E2) treatment. cnt, control.

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