Clinical situation | Recommendation |
---|---|
Dyspepsia | Empirical treatment with H2 receptor antagonist or PPI; individualize therapy |
Helicobacter pylori infection | Treatment to eradicate infection in patients with a history of peptic ulcer; PPI therapy |
Active gastroduodenal ulcer | Â |
   NSAID discontinued | Treatment with H2 receptor antagonist or a PPI |
   NSAID continued | Treatment with a PPI |
Prophylactic therapy | Treatment with a PPI or misoprostol or a COX-2 (preferential) or selective NSAID |