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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats

Figure 2

Morphological features and histopathological aspects of the hindlimb in AIA rats. (a) Control rats and (b) rats treated with tetrathiomolybdate (TM). Joint swelling, redness, and edema of the foot in AIA was clearly reduced with TM administration at day 17 after immunization. Histopathological studies using hematoxylin and eosin staining of the foot joint also revealed (c) a marked decrease of synovial inflammatory cell infiltrate and synovial lining hyperplasia compared with (d) control rats. (c), (d) Original magnification × 40. AIA, adjuvant-induced arthritis; MC, monocyte; SL, synovial lining cell; OC, osteoclast.

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Arthritis Research & Therapy

ISSN: 1478-6362

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