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Table 3 Genotype skewing of FCGR3A and FCGR2A gene polymorphisms in anti-GPI antibody positive healthy individuals

From: A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies

Polymorphism

Genotype

RA GPI+ (n = 23)

Healthy GPI+ (n = 9)

P (χ2)

P (Fisher's)

OR (95% CI)

FCGR3A-158

FF

10 (43.5%)

8 (88.9%)

0.019

0.044

0.09 (0.01–0.89)

 

FV/VV

13(56.5%)

1 (11.1%)

   

FCGR2A-131

HH

16 (69.6%)

4(44.4%)

0.19

0.24

2.86 (0.58–13.96)

 

HR/RR

7 (30.4%)

5 (55.6%)

   
  1. P values are given for RA versus healthy individuals using a 2×2 contingency table. CI, confidence interval; Fisher's, Fisher's probability test; OR, odds ratio; RA, rheumatoid arthritis.
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Arthritis Research & Therapy

ISSN: 1478-6362

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