Figure 6

ApoA-1 concentrations are decreased in non-active RA but correlate with the inhibitory serum activity in active RA. (a) Box plot depicting ApoA-1 concentrations in sera from healthy controls (n = 20), in patients with active RA (n = 20) and in patients with non-active disease (n = 20). Levels of significance are given; n.s., not significant. (b) Scatter plot depicting the correlation between ApoA-1 concentrations and inhibitory serum activity in sera from patients with active RA. Each data point represents the ApoA-1 concentration in relation to the inhibitory activity. Tumour necrosis factor (TNF)-α production in the co-culture system containing 10% FCS is set to 100%. The regression line illustrates the negative correlation between the two parameters (correlation coefficient R = -0.527; P = 0.016).