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Table 4 Indices of vitamin B status in patients with rheumatoid arthritis and control subjects

From: Inflammation causes tissue-specific depletion of vitamin B6

Component Patients (n = 33) Controls (n = 17) P
Plasma pyridoxal 5'-phosphate (nmol/L)a 24.7 (19.5–31.1) 46.2 (35.3–60.3) 0.001
Red blood cell pyridoxal 5'-phosphate (nmol/L packed red blood cells) 39.7 (34.2–45.2) 33.1 (24.4–41.7) 0.182
αEAST 1.8 (1.8–1.9) 1.9 (1.8–2.1) 0.242
Urinary 4-pyridoxic acid (μg/day)a 0.8 (0.6–1.0) 1.1 (0.9–1.6) 0.08
Plasma folate (μg/L)a 10.2 (8.4–12.5) 9.5 (7.9–11.3) 0.185
Red blood cell folate (μg/L)a 302 (262–347) 274 (226–333) 0.404
Vitamin B12 (ng/L)a 434 (390–496) 398 (334–473) 0.371
  1. Data are shown as geometric means and 95% confidence intervals. aData were log-transformed to achieve normality for statistical analysis. αEAST, erythrocyte aspartate aminotransferase activity coefficient. Bold P values are statistically significant.