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Table 4 Indices of vitamin B status in patients with rheumatoid arthritis and control subjects

From: Inflammation causes tissue-specific depletion of vitamin B6

Component

Patients (n = 33)

Controls (n = 17)

P

Plasma pyridoxal 5'-phosphate (nmol/L)a

24.7 (19.5–31.1)

46.2 (35.3–60.3)

0.001

Red blood cell pyridoxal 5'-phosphate (nmol/L packed red blood cells)

39.7 (34.2–45.2)

33.1 (24.4–41.7)

0.182

αEAST

1.8 (1.8–1.9)

1.9 (1.8–2.1)

0.242

Urinary 4-pyridoxic acid (μg/day)a

0.8 (0.6–1.0)

1.1 (0.9–1.6)

0.08

Plasma folate (μg/L)a

10.2 (8.4–12.5)

9.5 (7.9–11.3)

0.185

Red blood cell folate (μg/L)a

302 (262–347)

274 (226–333)

0.404

Vitamin B12 (ng/L)a

434 (390–496)

398 (334–473)

0.371

  1. Data are shown as geometric means and 95% confidence intervals. aData were log-transformed to achieve normality for statistical analysis. αEAST, erythrocyte aspartate aminotransferase activity coefficient. Bold P values are statistically significant.