Table 1 Genes whose mRNA expression is differentially expressed in bone marrow-derived or synovium-derived cells
Gene | Fold changes versus day 0 |
|---|---|
Upregulated in bone marrow-derived cells | |
MIP-1β | 40.5 |
IGF2 | 34.3 |
OX40 ligand | 27.5 |
Neuregulin | 26.8 |
Lymphotoxin-β | 13.5 |
Acidic fibroblast growth factor | 11.4 |
GAPDH | 11.3 |
Lymphotoxin-α precursor | 10.0 |
BIGH3 | 9.5 |
TRAIL | 7.2 |
IFN-γ receptor | 7.2 |
G-CSF | 6.9 |
Glia-derived neurite-promoting factor (GDNPF) | 6.4 |
IFN-α/β receptor β-subunit precursor | 6.2 |
Hepatocyte growth factor | 6.0 |
RPL13A | 5.9 |
Platelet-activating factor receptor | 5.6 |
Keratinocyte growth factor; FGF7 | 4.8 |
Endothelin receptor type A | 4.5 |
IGF-binding protein 2 (IGFBP2) | 4.1 |
Inhibin bA subunit precursor; activin bA subunit precursor | 4.1 |
Apoptosis-related protein TFAR15 | 4.0 |
Related to receptor tyrosine kinase (RYK) | 3.4 |
VEGFR1 | 3.3 |
IGF-binding protein 3 (IGFPB3) | 3.0 |
Insulin-like growth factor I receptor (IGF1R) | 2.9 |
Downregulated in bone marrow-derived cells | |
MIP2-α, GRO-β | -26.2 |
IL-8 precursor | -25.3 |
Tumor necrosis factor-inducible protein TSG-6 | -13.8 |
βNGF | -11.9 |
Granulocyte chemotactic protein (GCP2) | -6.2 |
FLT3 ligand | -5.1 |
Leukocyte IFN-inducible peptide | -4.9 |
BMP-4 + BMP-2B | -4.7 |
Activin receptor-like kinase 1 (Alk1); transforming growth factor beta superfamily receptor I (TSR1) | -4.2 |
Tumor necrosis factor alpha | -4.0 |
TRAIL receptor 2; death receptor 5 | -3.8 |
BMP3B; GDF10 | -3.6 |
Ciliary neurotropic factor receptor (CNTFR) | -3.6 |
Tumor necrosis factor receptor (TNFR) | -3.3 |
B-cell growth factor 1 precursos (BCGF1) | -3.2 |
IL-13 precursor | -3.1 |
Transforming growth factor beta | -2.8 |
IL-6 | -2.6 |
ERBB2 receptor protein-tyrosine kinase | -2.5 |
IFN regulatory factor | -2.3 |