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Table 1 Genes whose mRNA expression is differentially expressed in bone marrow-derived or synovium-derived cells

From: Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells

Gene Fold changes versus day 0
Upregulated in bone marrow-derived cells
   MIP-1β 40.5
   IGF2 34.3
   OX40 ligand 27.5
   Neuregulin 26.8
   Lymphotoxin-β 13.5
   Acidic fibroblast growth factor 11.4
   GAPDH 11.3
   Lymphotoxin-α precursor 10.0
   BIGH3 9.5
   TRAIL 7.2
   IFN-γ receptor 7.2
   G-CSF 6.9
   Glia-derived neurite-promoting factor (GDNPF) 6.4
   IFN-α/β receptor β-subunit precursor 6.2
   Hepatocyte growth factor 6.0
   RPL13A 5.9
   Platelet-activating factor receptor 5.6
   Keratinocyte growth factor; FGF7 4.8
   Endothelin receptor type A 4.5
   IGF-binding protein 2 (IGFBP2) 4.1
   Inhibin bA subunit precursor; activin bA subunit precursor 4.1
   Apoptosis-related protein TFAR15 4.0
   Related to receptor tyrosine kinase (RYK) 3.4
   VEGFR1 3.3
   IGF-binding protein 3 (IGFPB3) 3.0
   Insulin-like growth factor I receptor (IGF1R) 2.9
Downregulated in bone marrow-derived cells
   MIP2-α, GRO-β -26.2
   IL-8 precursor -25.3
   Tumor necrosis factor-inducible protein TSG-6 -13.8
   βNGF -11.9
   Granulocyte chemotactic protein (GCP2) -6.2
   FLT3 ligand -5.1
   Leukocyte IFN-inducible peptide -4.9
   BMP-4 + BMP-2B -4.7
   Activin receptor-like kinase 1 (Alk1); transforming growth factor beta superfamily receptor I (TSR1) -4.2
   Tumor necrosis factor alpha -4.0
   TRAIL receptor 2; death receptor 5 -3.8
   BMP3B; GDF10 -3.6
   Ciliary neurotropic factor receptor (CNTFR) -3.6
   Tumor necrosis factor receptor (TNFR) -3.3
   B-cell growth factor 1 precursos (BCGF1) -3.2
   IL-13 precursor -3.1
   Transforming growth factor beta -2.8
   IL-6 -2.6
   ERBB2 receptor protein-tyrosine kinase -2.5
   IFN regulatory factor -2.3
  1. Upregulation or downregulation refer to the fold increase higher than ratio 2 in bone marrow samples (n = 4) compared with synovial samples (n = 4), with a Mann-Whitney significance of 0.05.