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Table 1 Correlation between specific IgG-total and accumulative score

From: Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase

Strain Anti-hG6PI versus score Anti-CII versus score n
  Rho P value Rho P value  
C3H.NB 0.917* 0.009* 0.793* 0.026* 9
B10.Q 0.402* 0.046* -0.094 0.614 26
(B10.Q × DBA1)F1 0.018 0.956 0.139 0.67 10
DBA/1 0.317 0.370 0.033 0.924 10
  1. To investigate correlations between arthritis severity and antibody production the Spearman correlation test was applied. Mice of indicated strains were immunized with 200 μg glucose-6-phosphate isomerase (G6PI) in complete Freund's adjuvant. Blood was drawn at day 40 and analyzed by ELISA for anti-hG6PI and anti-CII total IgG responses, as shown in Fig. 1. The accumulative arthritis score until day 40 was tested for correlation with antibody production using the Spearman rank correlation test. A rho value close to 1 indicates correlation of high ranks for IgG with high ranks for arthritis scores; 0 indicates that there is no correlation between values; and a number close to -1 indicates that high ranks for one variable correlate with low ranks for the other. *Significant positive correlations.