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Table 1 Effects of peroxisome-proliferator-activated receptor γ agonists on viability of IL-1β-stimulated chondrocytes

From: Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)γ agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1β-stimulated rat chondrocytes: evidence for PPARγ-independent inhibition by 15-deoxy-Δ12,14prostaglandin J2

Agonist added A 580 Percentage of control
None (control) 0.81 ± 0.05 100
IL-1β (10 ng/ml) 1.12 ± 0.04* 138
15d-PGJ2 (10 μM) 0.91 ± 0.07 112
IL-1β + 15d-PGJ2 1.10 ± 0.05 135
Rosiglitazone (10 μM) 0.95 ± 0.09 117
IL-1β + rosiglitazone 1.12 ± 0.07 138
  1. 15d-PGJ2, 15-deoxy-Δ12,14prostaglandin J2.
  2. *, P < 0.05, comparison with non-stimulated controls