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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity

Figure 1

PONDR® predictions of disorder for four familiar human proteins. The SwissProt Accession Numbers [63] are given in parentheses. (a) Alpha-1-antitrypsin (P01009); (b) hemoglobin B (P02023); (c) calmodulin (P62158); (d) transthyretin precursor human (P02766). The line at PONDR® score 0.5 defines the disorder threshold and is an arbitrary measure used to distinguish order from disorder. The PONDR® predictor used here and in all other diagrams in this paper is VL-XT, which is the default predictor on the PONDR® web site.

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