Skip to main content
Figure 6 | Arthritis Research & Therapy

Figure 6

From: Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells

Figure 6

Suppressive effect of DHMEQ on inflammatory mediator production by RA-FLS at the protein level. Rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) were stimulated with tumour necrosis factor (TNF)-α in the presence or absence of 10 μg/ml dehydroxymethylepoxyquinomicin (DHMEQ), and levels of secreted CC chemokine ligand (CCL)2, CCL5, IL-6, and matrix metalloproteinase (MMP)-3 in the culture supernatants were measured using ELISA. Values are expressed as the mean ± standard deviation of three independent experiments.

Back to article page