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Table 2 Genotype frequencies in UK Caucasian and North Indian/Pakistani rheumatoid arthritis patients and healthy controls

From: Analysis of Fcγ receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B

Gene Genotype UK Caucasian North Indian/Pakistani
   Control (n = 129) RA (n = 147) P Nodular RA (n = 37) P Control (n = 128) RA (n = 123) P
FCGR2A-131 RR 39 (0.31) 40 (0.28) 0.81 7 (0.19) 0.36 25 (0.19) 30 (0.25) 0.15
  RH 59 (0.47) 72 (0.49)   21 (0.58)   66 (0.52) 48 (0.39)  
  HH 28 (0.22) 34 (0.23)   8 (0.22)   37 (0.29) 44 (0.36)  
FCGR3A-158 FF 68 (0.48) 59 (0.39) 0.15 12 (0.31) 0.02 63 (0.49) 48 (0.38) 0.21
  FV 61 (0.43) 69 (0.46)   17 (0.45)   57 (0.44) 66 (0.52)  
  VV 12 (0.09) 22 (0.15)   9 (0.24)   9 (0.07) 12 (0.10)  
FCGR3B-NA 22 48 (0.37) 55 (0.38) 0.13 16 (0.43) 0.28 49 (0.39) 47 (0.39) 0.25
  21 72 (0.56) 71 (0.48)   16 (0.43)   45 (0.35) 53 (0.43)  
  11 9 (0.07) 21 (0.14)   5 (0.14)   33 (0.26) 22 (0.18)  
FCGR2B-1206 GG 56 (0.48) 67 (0.46) 0.96 16 (0.43) 0.19 61 (0.48) 58 (0.47) 0.98
  GA 50 (0.42) 63 (0.43)   13 (0.35)   54 (0.43) 54 (0.44)  
  AA 12 (0.10) 16 (0.11)   8 (0.22)   11 (0.09) 11 (0.09)  
  1. Values are expressed as number (%). RA, rheumatoid arthritis.