Skip to main content

Table 2 Mean actual PID for 3-hour and 5-hour time points after first dose

From: First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]

Mean actual PID (10 mm VAS) Lumiracoxib 400 mg (n = 144) Celecoxib 200 mg (n = 145) Placebo (n = 75)
Mean ± SD 19.8 ± 16.5** 16.8 ± 15.9 13.4 ± 12.9
Median (range) 16.0 (-15.5, 74.5) 15.5 (-31.0, 58.5) 12.5 (-9.5, 48.5)
  1. **P = 0.004, pair-wise comparison versus placebo using least square means; P = 0.069, pair-wise comparison versus placebo using least square means. PID, pain intensity difference; SD, standard deviation; VAS, visual–analogue scale.