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Figure 1 | Arthritis Research & Therapy

Figure 1

From: THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis

Figure 1

Clinical disease activity of collagen-induced arthritis (CIA). DBA/1J mice were immunized with type II collagen and complete Freund's adjuvant (CFA) on days 0 and 21. The mice were then supplemented with THR0921 (50 mg/kg; open circles) or vehicle (closed circles) for 3 weeks. The clinical disease activity of CIA was determined every other day using a three-point scale for each paw. Data are expressed as mean ± standard error of the mean (n = 10/group; asterisks indicate p < 0.001 versus untreated-CIA mice).

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