Table 2 Frequency of HLA class II phenotypes
HLA | Controls | Polymyositis | Dermatomyositis |
|---|---|---|---|
n (%) | n (%) | n (%) | |
DRB1 | (n = 537) | (n = 115) | (n = 107) |
01 | 127 (23.6) | 25 (21.7) | 27 (25.2) |
02 | 145 (27.0) | 23 (20.0) | 19 (17.8) |
03 | 151 (28.1) | 72 (62.6) | 50 (46.7) |
04 | 195 (36.3) | 31 (27.0) | 39 (36.4) |
07 | 129 (24.0) | 11 (9.6) | 37 (34.6) |
08 | 37 (6.9) | 5 (4.3) | 2 (1.9) |
09 | 12 (2.2) | 1 (0.9) | 2 (1.9) |
10 | 8 (1.5) | 3 (2.6) | 0 (0) |
11 | 61 (11.4) | 16 (13.9) | 11 (10.3) |
12 | 11 (2.0) | 3 (2.6) | 1 (0.9) |
13 | 96 (17.9) | 18 (15.6) | 10 (9.3) |
14 | 30 (5.6) | 5 (4.3) | 5 (4.7) |
p | 0.0001 | 0.009 | |
DQA1 | (n = 142) | (n = 110) | (n = 104) |
01 | 92 (64.8) | 62 (56.4) | 57 (54.8) |
02 | 33 (23.2) | 10 (9.1) | 36 (34.6) |
03 | 60 (42.3) | 31 (28.2) | 39 (37.5) |
04 | 5 (3.5) | 3 (2.7) | 1 (1.0) |
05 | 55 (38.7) | 82 (74.5) | 58 (55.8) |
06 | 2 (1.4) | 2 (1.8) | 0 (0) |
p | 0.0001 | 0.02 | |
DQB1 | (n = 153) | (n = 116) | (n = 108) |
02 | 61 (39.9) | 76 (65.5) | 71 (65.7) |
03 | 87 (56.9) | 56 (48.3) | 57 (52.8) |
04 | 9 (5.9) | 5 (4.3) | 3 (2.8) |
05 | 42 (27.5) | 35 (30.2) | 32 (29.6) |
06 | 65 (42.5) | 37 (31.9) | 31 (28.7) |
p | 0.02 | 0.008 |