Relationship of DC numbers to acute phase response. Circulating myeloid dendritic cell (mDC) numbers are significantly inversely correlated to C-reactive protein (CRP) levels in rheumatoid arthritis (RA) peripheral blood (PB). The CRP levels of RA patients (n = 12) compared with total numbers of (a) mDCs and (b) plasmacytoid dendritic cells (pDCs) per millilitre of PB. CRP levels are calculated on a logarithmic scale, and squares indicate individual samples. *P < 0.05.