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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis

Figure 3

Phenotypic characterisation of blood derived DC subsets. Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) peripheral blood (PB) plasmacytoid dendritic cells (pDCs) and myeloid dendritic cells (mDCs) have an immature phenotype and significantly decreased CD62L expression. (a) Migration and maturation markers on CD1c+/CD11c+ mDCs purified from RA PB (n = 5) and from PsA PB (n = 5) compared with healthy control PB (n = 5). (b) CD303 (BDCA-2)+/CD123+ pDCs purified from RA PB (n = 5) and from PsA PB (n = 5) compared with healthy control PB (n = 5). Values are calculated as the mean fluorescent intensity (MFI) fold of the increase above the isotype control. The median and interquartile range is shown. *P < 0.05.

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