Figure 5

Phenotypic characterisation of synovial DC subsets. Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) synovial fluid (SF) plasmacytoid dendritic cells (pDCs) have an immature phenotype, but myeloid dendritic cells (mDCs) have a semi-mature phenotype. Migration and maturation markers on CD1c⁺/CD11c⁺ mDCs purified from (a) RA SF (n = 3) compared with RA peripheral blood (PB) (n = 5) and (b) PsA SF (n = 3) compared with PsA PB (n = 5), and CD303⁺/CD123⁺ pDCs purified from (c) RA SF (n = 3) compared with RA PB (n = 5) and (d) PsA SF (n = 3) compared with PsA PB (n = 5). Values are calculated as the mean fluorescent intensity (MFI) fold of the increase above the isotype control. The median and interquartile range are shown. *P < 0.05