Figure 3From: Partial protection against collagen antibody-induced arthritis in PARP-1 deficient miceMilder synovial inflammation and cartilage damage in poly(ADP-ribose) polymerase (PARP)-1 deficient mice than in control mice. Histopathological scoring of (a) synovial inflammation and (b) cartilage damage of knee joint sections of parp-1+mice and parp-1o/o mice at day 5 and 12 after induction of collagen antibody-induced arthritis. Values are expressed as mean ± standard error of the mean; p = 0.03, parp-1+ versus parp-1o/o mice by combined analysis of (a) and (b) (MANCOVA test).Back to article page