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Table 1 Semi-quantification of synovial apoptosis

From: Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthritis

Group Synovium P value
Saline (n = 4) 0.625 ± 0.479  
rTRAIL 5 μg (n = 4) 2.500 ± 1.000 0.022
rTRAIL 20 μg (n = 4) 3.000 ± 0.816 0.023
  1. A semi-quantitative scale was used to estimate the degree of TUNEL staining in synovial tissue sections. Investigators blindly reviewed primarily two areas: synovial lining and subsynovial regions. The extent of staining in these areas was scored on a scale of 0 to 4 as follows: 0, negative; 1+, rare positive apoptotic bodies; 2+, scattered clusters of positive apoptotic bodies; 3+, moderate staining; and 4+, extensive staining. Student's t test was used for a statistical analysis. rTRAIL, recombinant TRAIL protein.