Table 2 Sensitivity, specificity, 95% confidence intervals and likelihood ratios
Sensitivity | Specificity | Likelihood ratio | |||
|---|---|---|---|---|---|
% | 95% CI | % | 95% CI | ||
PTPN22 CT+TT | 39.3 | 29.6–49.7 | 80.3 | 75.9–84.1 | 2.0 |
Anti-CCP Abs | 37.1 | 27.5–47.5 | 98.6 | 96.9–99.5 | 26.2 |
IgG-RF | 16.9 | 8.9–28.1 | 95.8 | 92.6–97.8 | 4.0 |
IgA-RF | 42.4 | 30.3–55.2 | 94.9 | 91.5–97.2 | 8.3 |
IgM-RF | 22.0 | 12.8–33.9 | 94.1 | 90.5–96.6 | 3.7 |
SE (B1*0404 or 0401) | 55.6 | 45.2–65.6 | 61.8 | 54.4–68.9 | 1.5 |
SE + PTPN22 CT+TT | 24.1 | 16.0–34.0 | 92.9 | 88.3–96.1 | 3.4 |
Anti-CCP Abs + PTPN22 CT+TT | 22.1 | 14.3–31.8 | 100.0 | - | - |