Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes

Table 6 Baseline parameters predicting medial compartment cartilage volume loss at 24 months: stepwise forward multivariate regression

Variable entry number	Regression coefficient (beta)	T value	P value
1. Severe medial meniscal extrusion	-0.29	-3.54	<0.0001
2. Bone edema	-0.34	-2.31	0.02
3. SF-36 physical component	-0.20	-2.05	0.04
4. Total WOMAC	-0.45	-1.87	0.06

Variables used in the model: age, gender, weight, body mass index, Western Ontario McMaster Osteoarthritis Index (WOMAC) pain, function and total score, patient global scale, SF-36 physical component, baseline medial cartilage volume, meniscal tear and extrusion, bone edema, smoking, urinary C-terminal crosslinking telopeptide of collagen type II.

ISSN: 1478-6362