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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

Figure 5

Immunolocalisation of FAPĪ± protein in osteoarthritic (OA) cartilage. (a) FAPĪ± in OA cartilage specimen 1. Note positive staining (brown/black) of cells in the superficial zone. Boxed region represents low-power view of Figure 5b. (b) High-power view of FAPĪ± in OA cartilage specimen 1. Note positive staining of the chondrocyte membrane (arrow). (c) FAPĪ± in OA cartilage specimen 2. Note positive staining of cells in the superficial zone. (d) OA cartilage specimen 2 treated with non-immune mouse IgG as a negative control for FAPĪ±.

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