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Table 2 One year drug survival of first and second tumor necrosis factor antagonist, by diagnosis

From: Switching TNF antagonists in patients with chronic arthritis: an observational study of 488 patients over a four-year period

Diagnosis

Rank of treatment

Number starting

Number failed

Survival (95% CI)

Rheumatoid arthritis

First

2,235

518

0.83 (0.82–0.84)

 

Second

194

72

0.79 (0.74–0.83)

Ankylosing spondylitis

First

300

49

0.89 (0.86–0.92)

 

Second

8

1

0.95 (0.72–0.99)

Psoriatic arthritis

First

289

55

0.87 (0.83–0.90)

 

Second

15

8

0.81 (0.65–0.90)

Juvenile idiopathic arthritis

First

126

16

0.90 (0.84–0.94)

 

Second

7

7

0.49 (0.22–0.72)

  1. All differences between survival curves in first and second treatment for each diagnosis have a p > 0.001.