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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model

Figure 5

Biologic processes revealed by the present study and previously published murine studies. Genes identified by previous published studies were retrieved from the papers or from online supporting materials [11, 13-15]. Their rat orthologs were obtained by querying NCBI HomoloGene database. The retrieved gene symbols were mapped onto the Gene Ontology (GO) tree, in particular Biological Process, using GoMiner. Percentages of differentially expressed genes were calculated for the selected 10 biological processes at the third or the fourth GO levels and plotted. Note the overall similarity in Biological Process represented by the five independent studies.

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