Figure 5From: The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritisEffect of IB-MECA treatment on the expression level of key signaling proteins downstream to A3 adenosine receptor (A3AR) activation in synovia cells. The level of PI3K, pPKB/Akt, IKKα/β, NF-κB, TNF-α and caspase-3 was examined by western blot analysis. AIA, adjuvant-induced arthritis.Back to article page